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The best hotels in Buffalo Comfort Suites Downtown Buffalo Double room / night from £75 Holiday Inn Buffalo Double room / night from £75 Quality Inn Buffalo Airport Double room / night from £60 Adam's Mark Buffalo Double room / night from £82 Comfort Suites Buffalo Double room / night from £55 Days Hotel Airport Buffalo (New York) Double room / night from £69 Best Western On the Avenue Double room / night from £90 Hyatt Regency Buffalo Double room / night from £85 Econo Lodge South Buffalo (New York) Double room / night from £53 Hampton Inn & Suites Buffalo Downtown Double room / night from £108